2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Cholestenone-d5

Cholestenone-d5  (Synonyms: 4-Cholesten-3-one-d5)

製品番号: HY-113365S 純度: 98.04%
COA 取扱説明書 Technical Support

Cholestenone-d5 is the deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells.

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Cholestenone-d<sub>5</sub>

Cholestenone-d5 構造式

CAS 番号 : 72560-60-2

容量 価格（税別） 在庫状況 数量
1 mg $75 在庫あり
5 mg $250 在庫あり
25 mg $750 お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
50 mg   お問い合わせ  
100 mg   お問い合わせ  

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Cholestenone-d5 関連抗体

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製品説明

Cholestenone-d5 is the deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cholestenone-d5 関連抗体
分子量

389.67

分子式

C27H39D5O
CAS 番号
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C([2H])([2H])C3)=C([2H])C(C([2H])([2H])C4)=O)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

Ethanol : 50 mg/mL (128.31 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5663 mL 12.8314 mL 25.6627 mL
5 mM 0.5133 mL 2.5663 mL 5.1325 mL
10 mM 0.2566 mL 1.2831 mL 2.5663 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.42%

COA (250 KB) HNMR (853 KB) RP-HPLC (923 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 2.5663 mL 12.8314 mL 25.6627 mL 64.1568 mL
5 mM 0.5133 mL 2.5663 mL 5.1325 mL 12.8314 mL
10 mM 0.2566 mL 1.2831 mL 2.5663 mL 6.4157 mL
15 mM 0.1711 mL 0.8554 mL 1.7108 mL 4.2771 mL
20 mM 0.1283 mL 0.6416 mL 1.2831 mL 3.2078 mL
25 mM 0.1027 mL 0.5133 mL 1.0265 mL 2.5663 mL
30 mM 0.0855 mL 0.4277 mL 0.8554 mL 2.1386 mL
40 mM 0.0642 mL 0.3208 mL 0.6416 mL 1.6039 mL
50 mM 0.0513 mL 0.2566 mL 0.5133 mL 1.2831 mL
60 mM 0.0428 mL 0.2139 mL 0.4277 mL 1.0693 mL
80 mM 0.0321 mL 0.1604 mL 0.3208 mL 0.8020 mL
100 mM 0.0257 mL 0.1283 mL 0.2566 mL 0.6416 mL
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Cholestenone-d5 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cholestenone-d572560-60-24-Cholesten-3-one-d5Endogenous MetaboliteInhibitorinhibitorinhibit

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製品名:
Cholestenone-d5
製品番号:
HY-113365S
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