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Cat. No.: HY-111138R

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CZC-8004 (Standard)

Name: CZC-8004 (Standard)
Brand: MedChemExpress
SKU: HY-111138R
Availability: PreOrder

(Synonyms: CZC-00008004 (Standard))

CZC-8004 (Standard) is the analytical standard of CZC-8004 (HY-111138). This product is intended for research and analytical applications. CZC-8004 (CZC-00008004) is a pan-K_inase inhibitor. CZC-8004 has IC₅₀ values of 650 and 437 nM for EGFR WT and VEGFR2 V916M, respectively. CZC-8004 can be used in the study of cancer.

For research use only. We do not sell to patients.

CAS No.: 916603-07-1
Formula: C₁₇H₁₆FN₅
Molecular Weight:309.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CZC-8004 (Standard) Chemical Structure

CAS No.: 916603-07-1

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Top Publications Citing

Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

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Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 916603-07-1
Molecular Weight 309.34
Formula C₁₇H₁₆FN₅
SMILES

FC1=CN=C(NC2=CC=C(CN)C=C2)N=C1NC3=CC=CC=C3
Synonyms

CZC-00008004 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ying ZD, et, al. Integrated in silico-in vitro analysis of systematic kinase gatekeeper mutation effects on pan-kinase inhibitors in targeted liver cancer therapy. J Chin Chem Soc. 2020 Oct 29;1-10.

[2]. Deane FM, et, al. FD5180, a Novel Protein Kinase Affinity Probe, and the Effect of Bead Loading on Protein Kinase Identification. ACS Omega. 2017 Jul 31;2(7):3828-3838. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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