Dichlorphenamide disodium
Based on 2 publication(s) in Google Scholar
Dichlorphenamide (Diclofenamide) disodium is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research.
For research use only. We do not sell to patients.
- CAS No.: 76382-13-3
- Formula: C6H6Cl2N2Na2O4S2
- Molecular Weight:351.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Dichlorphenamide disodium
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male albino rabbits (approximately 2.5 kg)[1]
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Dosage:50 μL 10% aqueous solutions of dichlorphenamide sodium or 2 mg/kg, 6 mg/kg
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Administration:Eye drop of 50 μL or oral gavage of 2 mg/kg or 6 mg/kg，5 hours
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Result:Showed significant decrease in IOP at 30 min by instilling into eyes and decrease in IOP only at 1 h by orally after drug administration. And demonstrated that drug levels were significantly higher in the iris ciliary body and lower in the serum by instilling compared to oral administration.
Chemical Information
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CAS No. 76382-13-3
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Molecular Weight 351.14
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Formula C6H6Cl2N2Na2O4S2
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SMILES
O=S(C1=CC(Cl)=C(Cl)C(S(=O)(N)=O)=C1)(N)=O.[Na].[Na]
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Synonyms
Diclofenamide disodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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ACS Environ Au
Machine Learning-Assisted Recognition of Environmental Sulfur-Containing Chemicals in Nontargeted Mass Spectrometry Analysis of Inadequate Mass Resolution. [Abstract]2025 Aug 5;5(6):573-582. PMID: 41277996 -
EMBO Rep
2022 Jun 7;23(6):e53932. PMID: 35403787
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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