2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. Dichlorphenamide disodium

Dichlorphenamide disodium  (Synonyms: Diclofenamide disodium)

Cat. No.: HY-B0397A
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Dichlorphenamide (Diclofenamide) disodium is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research.

For research use only. We do not sell to patients.

Dichlorphenamide disodium Chemical Structure

Dichlorphenamide disodium Chemical Structure

CAS No. : 76382-13-3

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Dichlorphenamide disodium Related Antibodies

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Description

Dichlorphenamide (Diclofenamide) disodium is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research[1].

In Vivo

Dichlorphenamide disodium can reduce IOP locally in male albino rabbits[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male albino rabbits (approximately 2.5 kg)[1]
Dosage: 50 μL 10% aqueous solutions of dichlorphenamide sodium or 2 mg/kg, 6 mg/kg
Administration: Eye drop of 50 μL or oral gavage of 2 mg/kg or 6 mg/kg，5 hours
Result: Showed significant decrease in IOP at 30 min by instilling into eyes and decrease in IOP only at 1 h by orally after drug administration. And demonstrated that drug levels were significantly higher in the iris ciliary body and lower in the serum by instilling compared to oral administration.
Clinical Trial
Molecular Weight

351.14

Formula

C6H6Cl2N2Na2O4S2
CAS No.
SMILES

O=S(C1=CC(Cl)=C(Cl)C(S(=O)(N)=O)=C1)(N)=O.[Na].[Na]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Dichlorphenamide disodium Related Classifications

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Keywords:

Dichlorphenamide disodium76382-13-3Diclofenamide disodiumCarbonic AnhydraseCarbonate dehydrataseCarbonic anhydrase inhibitorGlaucomaEyesInhibitorinhibitorinhibit

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