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Cat. No.: HY-N3749

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Dihydroniloticin

Dihydroniloticin is a natural tirucallane-type triterpene.

For research use only. We do not sell to patients.

CAS No.: 115334-05-9
Formula: C₃₀H₅₀O₃
Molecular Weight:458.72

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Dihydroniloticin Chemical Structure

CAS No.: 115334-05-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Dihydroniloticin is a natural tirucallane-type triterpene^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	5.2 μM Compound: 22	Antiproliferative activity against human A549 cells assessed as reduction in cell viability by SRB assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability by SRB assay	[PMID: 38970504]
HL-60	IC₅₀	<10 μM Compound: 15	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 23734701]
KB	IC₅₀	4.8 μM Compound: 22	Antiproliferative activity against human KB cells assessed as reduction in cell viability by SRB assay Antiproliferative activity against human KB cells assessed as reduction in cell viability by SRB assay	[PMID: 38970504]
MCF7	IC₅₀	7.2 μM Compound: 22	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability by SRB assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability by SRB assay	[PMID: 38970504]
MDA-MB-231	IC₅₀	4.7 μM Compound: 22	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability by SRB assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability by SRB assay	[PMID: 38970504]
RAW264.7	IC₅₀	>20 μM Compound: 15	Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NO production after 18 hrs by Griess method Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NO production after 18 hrs by Griess method	[PMID: 23734701]

Chemical Information

CAS No. 115334-05-9
Molecular Weight 458.72
Formula C₃₀H₅₀O₃
SMILES

C[C@@]12C3=CC[C@](C(C)([C@@H](O)CC4)C)([H])[C@@]4(C)[C@@]3([H])CC[C@]1([C@@]([C@@H](C)C[C@H]([C@@]5([H])C(C)(C)O5)O)([H])CC2)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. H Liu, et al. New tirucallane-type triterpenes from Dysoxylum variabile. J Nat Prod. 2001 Feb;64(2):159-63. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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