1. Antibody-drug Conjugate/ADC Related
  2. Radionuclide-Drug Conjugates (RDCs)
  3. DTPA-tetra(tBu)ester

DTPA-tetra(tBu)ester is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy.

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DTPA-tetra(tBu)ester

DTPA-tetra(tBu)ester Chemical Structure

CAS No. : 180152-83-4

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Description

DTPA-tetra(tBu)ester is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy[1].

IC50 & Target

RDC Bifunctional Chelator

 

Molecular Weight

617.77

Formula

C30H55N3O10

CAS No.
Appearance

Oil

Color

Light yellow to yellow

SMILES

O=C(CN(CCN(CCN(CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (161.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6187 mL 8.0936 mL 16.1873 mL
5 mM 0.3237 mL 1.6187 mL 3.2375 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6187 mL 8.0936 mL 16.1873 mL 40.4681 mL
5 mM 0.3237 mL 1.6187 mL 3.2375 mL 8.0936 mL
10 mM 0.1619 mL 0.8094 mL 1.6187 mL 4.0468 mL
15 mM 0.1079 mL 0.5396 mL 1.0792 mL 2.6979 mL
20 mM 0.0809 mL 0.4047 mL 0.8094 mL 2.0234 mL
25 mM 0.0647 mL 0.3237 mL 0.6475 mL 1.6187 mL
30 mM 0.0540 mL 0.2698 mL 0.5396 mL 1.3489 mL
40 mM 0.0405 mL 0.2023 mL 0.4047 mL 1.0117 mL
50 mM 0.0324 mL 0.1619 mL 0.3237 mL 0.8094 mL
60 mM 0.0270 mL 0.1349 mL 0.2698 mL 0.6745 mL
80 mM 0.0202 mL 0.1012 mL 0.2023 mL 0.5059 mL
100 mM 0.0162 mL 0.0809 mL 0.1619 mL 0.4047 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DTPA-tetra(tBu)ester
Cat. No.:
HY-164592
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