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Cat. No.: HY-169995

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E3 Ligase Ligand-linker Conjugate 143

E3 Ligase Ligand-linker Conjugate 143 is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of ACBI3 (HY-157228).

For research use only. We do not sell to patients.

Formula: C₂₈H₃₇BrN₆O₅S
Molecular Weight:649.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

E3 Ligase Ligand-linker Conjugate 143 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

E3 Ligase Ligand-linker Conjugate 143 is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of ACBI3 (HY-157228)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 649.60
Formula C₂₈H₃₇BrN₆O₅S
SMILES

O=C([C@@H]1C[C@@H](O)CN1C([C@H](C(C)C)N2C=C(OCCCCBr)N=N2)=O)N[C@@H](CO)C3=CC=C(C=C3)C4=C(N=CS4)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Popow J, et al. Targeting cancer with small molecule pan-KRAS degraders[J]. bioRxiv, 2023: 2023.10. 24.563163.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

E3 Ligase Ligand-linker Conjugate 143

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E3 Ligase Ligand-linker Conjugate 143

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 Ligase Ligand-linker Conjugate 143 Related Classifications

HY-169995 Related Classifications

Bioz

Keywords

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