EGFR/ErbB-2 inhibitor-1
EGFR/ErbB-2 inhibitor-1 is a ErbB2/HER2 inhibitor.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1135150-79-6
- Fòrmula: C23H15ClFN3OS2
- Peso molecular:467.97
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
ErbB2/HER2[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
3.22 μM
Compound: 33
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Antiproliferative activity against human BT474 cells expressing ErbB2 after 72 hrs by CTG assay
Antiproliferative activity against human BT474 cells expressing ErbB2 after 72 hrs by CTG assay
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[PMID: 19111461] |
| HFF | IC50 |
9.72 μM
Compound: 33
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Antiproliferative activity against HFF after 72 hrs by CTG assay
Antiproliferative activity against HFF after 72 hrs by CTG assay
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[PMID: 19111461] |
| HN5 | IC50 |
10.08 μM
Compound: 33
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Antiproliferative activity against human HN5 cells expressing EGFR after 72 hrs by CTG assay
Antiproliferative activity against human HN5 cells expressing EGFR after 72 hrs by CTG assay
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[PMID: 19111461] |
Chemical Information
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No. CAS 1135150-79-6
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Peso molecular 467.97
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Fòrmula C23H15ClFN3OS2
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SMILES
FC1=CC=CC(COC2=CC=C(NC3=C4C=C(C5=CC=CS5)SC4=NC=N3)C=C2Cl)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR/ErbB-2 inhibitor-1 Related Classifications
HY-156639 Related Classifications
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