EGFR WT/T790M/L858R-IN-1

Cat. No.: HY-162062: Data Sheet Handling Instructions
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EGFR WT/T790M/L858R-IN-1 (compound 10d) is a potent EGFR inhibitor, with IC₅₀s of 0.097, 0.280, and 0.051?μM for EGFR^WT, EGFR^T790M, and EGFR^L858R, respectively. EGFR WT/T790M/L858R-IN-1 can be used for the research of cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

EGFR WT/T790M/L858R-IN-1 화학구조

사이즈		재고
MOQ		Minimum order quantity
50 mg		견적 받기
100 mg		견적 받기
250 mg		견적 받기
Other size		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
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고객리뷰

제품 설명	EGFR WT/T790M/L858R-IN-1 (compound 10d) is a potent EGFR inhibitor, with IC₅₀s of 0.097, 0.280, and 0.051?μM for EGFR^WT, EGFR^T790M, and EGFR^L858R, respectively. EGFR WT/T790M/L858R-IN-1 can be used for the research of cancer^[1].
분자량	519.85
화학식	C₂₆H₂₅Cl₃N₂O₃
SMILES	ClC1=CC(Cl)=C(C2C(C(CC(C)(C)C3)=O)=C3N(C4=CC=C(Cl)C=C4)C(N)=C2C(OCC)=O)C=C1
선적	Room temperature in continental US; may vary elsewhere.
보관	Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서	Data Sheet (270 KB) Handling Instructions (2659 KB)
References	[1]. Al-Hamd MGA, et, al. Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFRWT, EGFRT790M, and EGFRL858R). J Enzyme Inhib Med Chem. 2023 Dec;38(1):2241674. [Content Brief]

EGFR WT/T790M/L858R-IN-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR WT/T790M/L858R-IN-1EGFREpidermal growth factor receptorErbB-1HER1EGFRWTEGFRT790MEGFRL858RInhibitorinhibitorinhibit

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EGFR WT/T790M/L858R-IN-1

EGFR WT/T790M/L858R-IN-1 Related Antibodies

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Biological Activity

순도&문서

References

고객리뷰

EGFR WT/T790M/L858R-IN-1 Related Classifications

몰농도 계산기

농도 희석 계산기