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Cat. No.: HY-P7060

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NT 13

(Synonyms: TPPT)

NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

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CAS No.: 117928-93-5
Formule: C₁₈H₃₀N₄O₇
Masse moléculaire:414.45

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NT 13 Chemical Structure

CAS No.: 117928-93-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Solvant et solubilité
- In Vitro
Pureté et documentation
Références
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target

Target: NMDAR^[1]

Voir tous les produits spécifiques à Isoform iGluR :

In Vitro

NT 13 derivatives are used in the study of depression, anxiety, and other related diseases. Some NT 13 derivatives are NMDAR partial agonist^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 117928-93-5
Masse moléculaire 414.45
Formule C₁₈H₃₀N₄O₇
Synonyms

TPPT
Sequence

Thr-Pro-Pro-Thr
Sequence Shortening

TPPT
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvant et solubilité

In Vitro:

DMSO : ≥ 122.5 mg/mL (295.57 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.4128 mL

12.0642 mL

24.1284 mL

5 mM

0.4826 mL

2.4128 mL

4.8257 mL

10 mM

0.2413 mL

1.2064 mL

2.4128 mL

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (278 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Moskal J. Methods of treating depression and other related diseases. US9340576B2

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.4128 mL	12.0642 mL	24.1284 mL	60.3209 mL
	5 mM	0.4826 mL	2.4128 mL	4.8257 mL	12.0642 mL
	10 mM	0.2413 mL	1.2064 mL	2.4128 mL	6.0321 mL
	15 mM	0.1609 mL	0.8043 mL	1.6086 mL	4.0214 mL
	20 mM	0.1206 mL	0.6032 mL	1.2064 mL	3.0160 mL
	25 mM	0.0965 mL	0.4826 mL	0.9651 mL	2.4128 mL
	30 mM	0.0804 mL	0.4021 mL	0.8043 mL	2.0107 mL
	40 mM	0.0603 mL	0.3016 mL	0.6032 mL	1.5080 mL
	50 mM	0.0483 mL	0.2413 mL	0.4826 mL	1.2064 mL
	60 mM	0.0402 mL	0.2011 mL	0.4021 mL	1.0053 mL
	80 mM	0.0302 mL	0.1508 mL	0.3016 mL	0.7540 mL
	100 mM	0.0241 mL	0.1206 mL	0.2413 mL	0.6032 mL

Keywords

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Solvant et solubilité
- In Vitro
Pureté et documentation
Références

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NT 13

Voir tous les produits spécifiques à Isoform iGluR

Activité biologique

Chemical Information

Solvant et solubilité

Pureté et documentation

Références

Help & FAQs

Complete Stock Solution Preparation Table

NT 13 Related Classifications

HY-P7060 Related Classifications