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Referencia número: HY-183534

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CDK2-IN-58

CDK2-IN-58 is a selective cyclin-dependent kinase 2 (CDK2) inhibitor with an IC₅₀ of 0.21 μM. CDK2-IN-58 can be used for cancer research.

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No. CAS: 328061-33-2
Fòrmula: C₁₈H₁₅N₅
Peso molecular:301.35

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK2-IN-58 Chemical Structure

No. CAS: 328061-33-2

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Actividad biológica

Descripciòn

CDK2-IN-58 is a selective cyclin-dependent kinase 2 (CDK2) inhibitor with an IC₅₀ of 0.21 μM. CDK2-IN-58 can be used for cancer research^[1].

IC₅₀ & Target^[1]

CDK2

0.21 μM (IC₅₀)

Ver todos los productos específicos de isoformas CDK :

In Vitro

CDK2-IN-58 (Compound 1a) inhibits CDK2-cyclin E enzyme activity with an IC₅₀ of 0.21 μM in a cell-free scintillation proximity assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 328061-33-2
Peso molecular 301.35
Fòrmula C₁₈H₁₅N₅
SMILES

N1=CC=C(N=C1NC=2C=CC=CC2)C3=C(N=C4C=CC=CN43)C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Byth KF, et al. Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors. Bioorg Med Chem Lett. 2004 May 3;14(9):2245-8. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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CDK2-IN-58

Ver todos los productos específicos de isoformas CDK

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

CDK2-IN-58 Related Classifications

HY-183534 Related Classifications