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Referencia número: HY-155952

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LOC1886

Name: LOC1886
Brand: MedChemExpress
SKU: HY-155952
Price: 122.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

LOC1886 is a covalent inhibitor of GPX4 with slightly lower potency than RSL3 and ML162.

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 98.03%
No. CAS: 951948-38-2
Fòrmula: C₁₃H₁₁N₃O₂
Peso molecular:241.25

Almacenamiento:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

LOC1886 Chemical Structure

No. CAS: 951948-38-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

LOC1886 is a covalent inhibitor of GPX4 with slightly lower potency than RSL3 and ML162^[1].

Ver todos los productos específicos de isoformas Glutathione Peroxidase :

GPX1
GPX4

Chemical Information

No. CAS 951948-38-2
Appearance Solid
Peso molecular 241.25
Fòrmula C₁₃H₁₁N₃O₂
Color White to off-white
SMILES

O=C(N1C=NC=C1)C2=CC3=C(N2)C=CC=C3OC
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Liu H, et al. Small-molecule allosteric inhibitors of GPX4. Cell Chem Biol. 2022 Dec 15;29(12):1680-1693.e9. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
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Chemical Information
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LOC1886

Ver todos los productos específicos de isoformas Glutathione Peroxidase

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

LOC1886 Related Classifications

HY-155952 Related Classifications

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