1. Metabolic Enzyme/Protease
  2. Glutathione Peroxidase
  3. MPO-IN-28

MPO-IN-28 

Cat. No.: HY-115486 Purity: 98.10%
Handling Instructions

MPO-IN-28 (Compound 28) is a myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM.

For research use only. We do not sell to patients.

MPO-IN-28 Chemical Structure

MPO-IN-28 Chemical Structure

CAS No. : 37836-90-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 385 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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Description

MPO-IN-28 (Compound 28) is a myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM.

Molecular Weight

231.25

Formula

C₁₁H₁₃N₅O

CAS No.

37836-90-1

SMILES

NC(NC1=NC(C)=C2C=CC(OC)=CC2=N1)=N

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 22.73 mg/mL (98.29 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3243 mL 21.6216 mL 43.2432 mL
5 mM 0.8649 mL 4.3243 mL 8.6486 mL
10 mM 0.4324 mL 2.1622 mL 4.3243 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (8.99 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (8.99 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (8.99 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
MPO-IN-28
Cat. No.:
HY-115486
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