Petasin

Petasin inhibits adipogenesis in cell 3T3-F442A with an IC50 of 0.95 μM. Petasin inhibits the expression of lipid synthesis factors ACC1, FAS and SCD1 by inhibiting transcription factors PPARγ and C/EBPα, as well as targeting TRPA1 and TRPV1 channels . Petasin inhibits mitochondrial complex I, thereby inhibiting tumor growth and metastasis. Petasin activates AMPK signaling pathway, participating in regulation of glucose and lipid metabolism. Petasin is orally active.

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  • No. CAS: 26577-85-5
  • Fòrmula: C20H28O3
  • Peso molecular:316.43
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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