Z32439948
Z32439948 is a butyrylcholinesterase (BChE) inhibitor (IC50: 1.4 μM, hBChE) and is a derivative of m-sulfamoylbenzamide. Z32439948 also exhibited neuroprotective effects against glutamate in SH-SY5Y cells.
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- No. CAS: 920845-86-9
- Fòrmula: C25H26N4O4S
- Peso molecular:478.56
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
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BChE 1.4 μM (IC50, [1]) |
In Vitro
Z32439948 (1-5 μM; 48 h) has neuroprotective effects on glutamate (31 mM)-induced SH-SY5Y cell death[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SH-SY5Y, BV2 cells
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Concentration:1 μM, 2 μM, 5 μM
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Incubation Time:48 h; with or without 31 mM Glutamate
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Result:Protected cell from Glutamate induced damage.
Chemical Information
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No. CAS 920845-86-9
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Peso molecular 478.56
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Fòrmula C25H26N4O4S
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SMILES
O=C(NCCC1=CNC2=C1C=CC=C2)C3=CC=C(OC)C(S(NCCC4=NC=CC=C4)(=O)=O)=C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Z32439948 Related Classifications
HY-162340 Related Classifications
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