PDE1A - phosphodiesterase 1A Gene

Species: Macaca fascicularis

Gene Type: protein coding
Gene ID: 102132529

About PDE1A

Primary_assembly 12: 69,664,736-70,066,564 reverse strand.Macaca_fascicularis_6.0:CM021950.1

This gene has 7 transcripts (splice variants), 208 orthologues and 20 paralogues.

PDE1A Products (11)

mRNA Protein Name
XM_045367348.1 XP_045223283.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X3
XM_005573638.3 XP_005573695.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X2
XM_005573639.3 XP_005573696.2 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1
XM_045367346.1 XP_045223281.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1
XM_045367349.1 XP_045223284.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X7
XM_005573642.3 XP_005573699.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X6
XM_015432455.2 XP_015287941.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X5
XM_045367347.1 XP_045223282.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1
XM_045367344.1 XP_045223279.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1
XM_015432454.2 XP_015287940.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X4
XM_045367345.1 XP_045223280.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1

PDE1A Protein Structure

PDEase_I_N

PDEase_I_N: pfam08499 (72 - 132)

PDEase_I

PDEase_I: pfam00233 (217 - 438)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 545 a.a.
Protein Preferred Names Protein Names

calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

  • phosphodiesterase 1A, calmodulin-dependent

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-12501A ITI-214 Inhibitor 99.56% Phase 2
HY-112831 Osoresnontrine Inhibitor 99.94% Phase 2
HY-12501 ITI-214 free base Inhibitor 98.0% Phase 2
HY-111167 AN-2898 Inhibitor / Phase 2
HY-103493 TAK-915 Inhibitor 99.57% Phase 1

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-136569 DSR-141562 Inhibitor 99.98% Unkown
HY-101490 PDE1-IN-2 Inhibitor 98.0% Unkown
HY-120741 PF-04822163 Inhibitor / Unkown
HY-120195 PF-04677490 Inhibitor / Unkown
HY-120195A PF-04827736 Inhibitor / Unkown
HY-147946 PDE1-IN-4 Inhibitor / Unkown
HY-RS10208 PDE1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10209 Pde1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10210 PDE1A Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE1A NCBI NCBI:5136