Pdzd8 - PDZ domain containing 8 Gene

Also Known as Pdzk8; A630041P07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 107368

Summary

Predicted to enable lipid binding activity and metal ion binding activity. Involved in mitochondrial calcium ion homeostasis and mitochondrion-endoplasmic reticulum membrane tethering. Located in endoplasmic reticulum membrane and mitochondria-associated endoplasmic reticulum membrane. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; gut; and retina nuclear layer. Orthologous to human PDZD8 (PDZ domain containing 8). [provided by Alliance of Genome Resources, Apr 2022]

Pdzd8 Products (1)

mRNA Protein Name
NM_001033222.3 NP_001028394.2 PDZ domain-containing protein 8

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in mitochondrial calcium ion homeostasis IDA
IDA: Inferred from direct assay
29097544 MGI
involved in mitochondrion-endoplasmic reticulum membrane tethering IDA
IDA: Inferred from direct assay
29097544 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
29097544 MGI
located in mitochondria-associated endoplasmic reticulum membrane contact site IDA
IDA: Inferred from direct assay
29097544 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PDZ domain-containing protein 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10304 PDZD8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21687 Pdzd8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28205 Pdzd8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdzd8 NCBI NCBI:118987