RAB40B - RAB40B, member RAS oncogene family Gene

Also Known as RAR; SEC4L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10966

About RAB40B

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:82,654,973-82,698,698 (from NCBI)

This gene has 11 transcripts (splice variants), 166 orthologues and 68 paralogues. Ubiquitous expression in brain (RPKM 11.7), kidney (RPKM 5.9) and 23 other tissues.

Summary

The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008]

RAB40B Products (1)

mRNA Protein Name
NM_006822.3 NP_006813.1 ras-related protein Rab-40B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in cellular detoxification IMP
IMP: Inferred from mutant phenotype
22042847 GOA
Cellular Component GO Annotation Evidence References Source
located in nuclear envelope IDA
IDA: Inferred from direct assay
22042847 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
22042847 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB40B Protein Structure

Ras

Ras: Ras family (16 - 174)

SOCS_box

SOCS_box: SOCS box (189 - 223)

  • 0
  • 100
  • 200
  • 278 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-40B

  • GTP-binding protein homologous to Saccharomyces cerevisiae SEC4

Related Diseases

Diseases Alias
Buschke-Ollendorff Syndrome

  • BOS

  • Dermatoosteopoikilosis

  • Dermatofibrosis Lenticularis Disseminata With Osteopoikilosis

  • Osteopathia Condensans Disseminata

  • Dermatofibrosis Lenticularis Disseminata

  • Disseminated Dermatofibrosis With Osteopoikilosis

  • Dermatofibrosis, Disseminated, With Osteopoikilosis

  • Osteopoikilosis With Or Without Melorheostosis

  • Dermatofibrosis, Disseminated With Osteopoikilosis

  • Dermatofibrosis Disseminata Lenticularis

  • Isolated Osteopoikilosis

  • Osteopoikilosis, Isolated
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11563 RAB40B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RAB40B RGD RGD:1305663
Mus musculus RAB40B MGD MGI:2183451
Bos taurus RAB40B VGNC VGNC:107274
Felis catus RAB40B VGNC VGNC:99427
Macaca mulatta RAB40B VGNC VGNC:81543
Others RAB40B NCBI