TADA1 - transcriptional adaptor 1 Gene

Also Known as ADA1; HFI1; hADA1; STAF42; TADA1L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 117143

About TADA1

Cytogenetic location: 1q24.1 Genomic coordinates (GRCh38): 1:166,856,510-166,876,264 (from NCBI)

This gene has 2 transcripts (splice variants) and 207 orthologues. Ubiquitous expression in brain (RPKM 9.2), bone marrow (RPKM 7.8) and 25 other tissues.

Summary

TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]

TADA1 Products (1)

mRNA Protein Name
NM_053053.4 NP_444281.1 transcriptional adapter 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transcription coactivator activity IDA
IDA: Inferred from direct assay
11564863 GOA
Cellular Component GO Annotation Evidence References Source
part of SAGA complex IDA
IDA: Inferred from direct assay
11564863 GOA
located in nucleus IDA
IDA: Inferred from direct assay
11564863 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TADA1 Protein Structure

SAGA-Tad1

SAGA-Tad1: Transcriptional regulator of RNA polII, SAGA, subunit (7 - 195)

  • 0
  • 100
  • 200
  • 300
  • 335 a.a.
Protein Preferred Names Protein Names

transcriptional adapter 1

  • SPT3-associated factor 42 (STAF42)

Related Diseases

Diseases Alias
Retinitis Pigmentosa 39

  • RP39

  • Retinitis Pigmentosa, Type 39
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14153 TADA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14753 TMEM98 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21777 Tada1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TADA1 VGNC VGNC:47069
Macaca mulatta TADA1 VGNC VGNC:78246
Felis catus TADA1 VGNC VGNC:65922
Rattus norvegicus TADA1 RGD RGD:1306774
Mus musculus TADA1 MGD MGI:1196415
Bos taurus TADA1 VGNC VGNC:35564
Others TADA1 NCBI