Flvcr2 - feline leukemia virus subgroup C cellular receptor 2 Gene

Also Known as CCT; Mfsd7c

Species: Mus musculus

Gene Type: protein coding
Gene ID: 217721

Summary

Predicted to enable heme binding activity and heme transmembrane transporter activity. Predicted to be involved in heme export. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including central nervous system and yolk sac. Used to study proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Human ortholog(s) of this gene implicated in proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Orthologous to human FLVCR2 (FLVCR heme transporter 2). [provided by Alliance of Genome Resources, Apr 2022]

Flvcr2 Products (1)

mRNA Protein Name
NM_145447.2 NP_663422.1 feline leukemia virus subgroup C receptor-related protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables choline binding IDA
IDA: Inferred from direct assay
38693257 MGI
enables choline transmembrane transporter activity IDA
IDA: Inferred from direct assay
38302740 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
32973183 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
32369453 MGI
involved in choline transport IDA
IDA: Inferred from direct assay
38693257 MGI
acts upstream of or within choline transport IMP
IMP: Inferred from mutant phenotype
38693257 MGI
acts upstream of or within endothelial tip cell fate specification IMP
IMP: Inferred from mutant phenotype
32369453 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
32369453 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
32369453 MGI
acts upstream of or within sprouting angiogenesis IMP
IMP: Inferred from mutant phenotype
32369453 MGI
involved in transport across blood-brain barrier IDA
IDA: Inferred from direct assay
38302740 MGI
acts upstream of or within transport across blood-brain barrier IMP
IMP: Inferred from mutant phenotype
38693257 MGI
Cellular Component GO Annotation Evidence References Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
38302740 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

feline leukemia virus subgroup C receptor-related protein 2

  • calcium-chelate transporter

  • feline leukemia virus subgroup C cellular receptor family, member 2

  • major facilitator superfamily domain containing 7C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04998 FLVCR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21132 Flvcr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27650 Flvcr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Flvcr2 NCBI NCBI:55640