DDIAS - DNA damage induced apoptosis suppressor Gene

Homo sapiens

Also known as noxin; C11orf82

Gene ID: 220042 | Gene type: protein coding

About DDIAS

Cytogenetic location: 11q14.1 Genomic coordinates (GRCh38): 11:82,901,736-82,934,659 (from NCBI)

This gene has 12 transcripts (splice variants) and 92 orthologues. Broad expression in testis (RPKM 5.9), lymph node (RPKM 1.9) and 14 other tissues.

Summary

Involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and regulation of DNA stability. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DDIAS Products(2)

mRNA	Protein	Name
NM_001363481.2	NP_001350410.1	DNA damage-induced apoptosis suppressor protein
NM_145018.4	NP_659455.3	DNA damage-induced apoptosis suppressor protein

Protein Preferred Names

Protein Names

DNA damage-induced apoptosis suppressor protein

nitric oxide-inducible gene protein

Related Diseases

Diseases

Alias

Fanconi Anemia, Complementation Group I

Fanconi Anemia Complementation Group I

FANCI

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03613	DDIAS Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	DDIAS	VGNC	VGNC:71718
Mus musculus	DDIAS	MGD	MGI:1921291
Bos taurus	DDIAS	VGNC	VGNC:27946
Rattus norvegicus	DDIAS	RGD	RGD:1559690
Canis familiaris	DDIAS	VGNC	VGNC:39835
Felis catus	DDIAS	VGNC	VGNC:82007

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