DDIAS - DNA damage induced apoptosis suppressor Gene

Also Known as noxin; C11orf82

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 220042

About DDIAS

Cytogenetic location: 11q14.1 Genomic coordinates (GRCh38): 11:82,901,736-82,934,659 (from NCBI)

This gene has 12 transcripts (splice variants) and 92 orthologues. Broad expression in testis (RPKM 5.9), lymph node (RPKM 1.9) and 14 other tissues.

Summary

Involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and regulation of DNA stability. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DDIAS Products (2)

mRNA Protein Name
NM_001363481.2 NP_001350410.1 DNA damage-induced apoptosis suppressor protein
NM_145018.4 NP_659455.3 DNA damage-induced apoptosis suppressor protein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: Inferred from mutant phenotype
24214091 GOA
involved in regulation of DNA stability IMP
IMP: Inferred from mutant phenotype
24214091 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA damage-induced apoptosis suppressor protein

  • nitric oxide-inducible gene protein

Related Diseases

Diseases Alias
Fanconi Anemia, Complementation Group I

  • Fanconi Anemia Complementation Group I

  • FANCI
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03613 DDIAS Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta DDIAS VGNC VGNC:71718
Mus musculus DDIAS MGD MGI:1921291
Bos taurus DDIAS VGNC VGNC:27946
Rattus norvegicus DDIAS RGD RGD:1559690
Canis familiaris DDIAS VGNC VGNC:39835
Felis catus DDIAS VGNC VGNC:82007
Others DDIAS NCBI