Ttf1 - transcription termination factor, RNA polymerase I Gene

Also Known as TTF-1; TTF-I

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22130

Summary

Enables DNA binding activity and chromatin binding activity. Acts upstream of or within chromatin remodeling; termination of RNA polymerase I transcription; and transcription initiation from RNA polymerase I promoter. Located in nucleus. Is expressed in early conceptus and genitourinary system. Orthologous to human TTF1 (transcription termination factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ttf1 Products (1)

mRNA Protein Name
NM_009442.2 NP_033468.2 transcription termination factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
7720715 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
9049305 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10589839 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within chromatin remodeling IDA
IDA: Inferred from direct assay
9049305 MGI
acts upstream of or within termination of RNA polymerase I transcription IDA
IDA: Inferred from direct assay
7720715 MGI
involved in termination of RNA polymerase I transcription IDA
IDA: Inferred from direct assay
10589839 MGI
involved in transcription by RNA polymerase I IDA
IDA: Inferred from direct assay
20513429 MGI
acts upstream of or within transcription initiation at RNA polymerase I promoter IDA
IDA: Inferred from direct assay
7720715 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleolus IDA
IDA: Inferred from direct assay
20513429 MGI
located in nucleoplasm IDA
IDA: Inferred from direct assay
20513429 MGI
located in nucleus IDA
IDA: Inferred from direct assay
7720715 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription termination factor 1

  • RNA polymerase I termination factor

  • transcription termination factor I

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09327 NKX2-1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15222 TTF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21450 Ttf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27968 Ttf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttf1 NCBI NCBI:7270