Cnr1 - cannabinoid receptor 1 Gene

Rattus norvegicus

Also known as SKR6R

Gene ID: 25248 | Gene type: protein coding

About Cnr1

Primary_assembly 5: 48,408,574-48,435,099 forward strand.mRatBN7.2:CM026978.1

This gene has 4 transcripts (splice variants), 206 orthologues, 18 paralogues and is associated with 57 phenotypes. Biased expression in Brain (RPKM 374.6), Adrenal (RPKM 99.1) and 2 other tissues.

Summary

Enables Cannabinoid Receptor activity. Involved in several processes, including positive regulation of acute inflammatory response; regulation of secretion by cell; and response to alkaloid. Located in membrane raft and plasma membrane. Colocalizes with intracellular membrane-bounded organelle. Used to study several diseases, including Parkinsonism; diabetic neuropathy; impotence; obesity; and peptic ulcer disease. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in obesity; schizophrenia; and type 2 diabetes mellitus. Orthologous to human CNR1 (Cannabinoid Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Cnr1 Products(1)

mRNA	Protein	Name
NM_012784.5	NP_036916.1	cannabinoid receptor 1

Cnr1 Protein Structure

7tmA_CB1

0
100
200
300
400
473 a.a.

Protein Preferred Names

Protein Names

cannabinoid receptor 1

CB-R	CB1
brain-type cannabinoid receptor	cannabinoid receptor 1 (brain)

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS02914	CNR1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS02915	Cnr1 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS02916	Cnr1 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cnr1	NCBI	NCBI:1268

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