Sfpq - splicing factor proline and glutamine rich Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 252855

Summary

Predicted to enable several functions, including chromatin binding activity; histone deacetylase binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including alternative mRNA splicing, via spliceosome; dendritic transport of messenger ribonucleoprotein complex; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromosome organization; double-strand break repair via homologous recombination; and positive regulation of sister chromatid cohesion. Predicted to be located in chromatin; nuclear matrix; and paraspeckles. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Orthologous to human SFPQ (splicing factor proline and glutamine rich). [provided by Alliance of Genome Resources, Apr 2022]

Sfpq Products (1)

mRNA Protein Name
NM_001025271.1 NP_001020442.1 splicing factor, proline- and glutamine-rich

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19874820 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

splicing factor, proline- and glutamine-rich

  • NonO/p54nrb homolog

  • splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)

  • splicing factor proline/glutamine-rich

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12770 SFPQ Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22321 Sfpq Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28843 Sfpq Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sfpq NCBI NCBI:6421