UNCX - UNC homeobox Gene

Homo sapiens

Also known as UNCX4.1

Gene ID: 340260 | Gene type: protein coding

About UNCX

This gene has 1 transcript (splice variant), 249 orthologues and 50 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a homeobox transcription factor that is involved in somitogenesis and neurogenesis and is required for the maintenance and differentiation of specific elements of the axial skeleton. This gene also plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and deliver Hormones that control peripheral functions. The expression of this gene is associated with an increased frequency of acute myeloid leukemia. [provided by RefSeq, Jul 2017]

UNCX Products(1)

mRNA	Protein	Name
NM_001080461.3	NP_001073930.1	homeobox protein unc-4 homolog

UNCX Protein Structure

Homeobox

0
100
200
300
400
500
531 a.a.

Protein Preferred Names

Protein Names

homeobox protein unc-4 homolog

UNC homeobox protein

Related Diseases

Diseases

Alias

Spondylocostal Dysostosis

Jarcho-Levin Syndrome	Costovertebral Dysplasia
Spondylothoracic Dysostosis	Spondylothoracic Dysplasia
Scdo	Dysostosis, Spondylocostal

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15477	UNCX Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	UNCX	MGD	MGI:108013
Rattus norvegicus	UNCX	RGD	RGD:69361
Macaca mulatta	UNCX	VGNC	VGNC:81789
Felis catus	UNCX	VGNC	VGNC:107827
Canis familiaris	UNCX	VGNC	VGNC:48146
Bos taurus	UNCX	VGNC	VGNC:58424