Snta1 - syntrophin, alpha 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 362242

Summary

Enables PDZ domain binding activity. Predicted to be involved in several processes, including negative regulation of peptidyl-cysteine S-nitrosylation; regulation of ion transmembrane transport; and ventricular cardiac muscle cell action potential. Predicted to act upstream of or within neuromuscular junction development and regulation of vasoconstriction by circulating norepinephrine. Located in neuromuscular junction and sarcolemma. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 12; and sudden infant death syndrome. Orthologous to human SNTA1 (syntrophin alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Snta1 Products (1)

mRNA	Protein	Name
NM_001100901.1	NP_001094371.1	alpha-1-syntrophin

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables PDZ domain binding	IPI IPI: Inferred from physical interaction	15024025	RGD

Cellular Component GO Annotation	Evidence	References	Source
located in neuromuscular junction	IDA IDA: Inferred from direct assay	7819523	RGD
located in sarcolemma	IDA IDA: Inferred from direct assay	7819523	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
alpha-1-syntrophin	syntrophin, acidic 1

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13512	SNTA1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22813	Snta1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS29328	Snta1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Snta1	NCBI	NCBI:6640