TRIM67 - tripartite motif containing 67 Gene
Also Known as TNL
Species: Homo sapiens
About TRIM67
This gene has 3 transcripts (splice variants), 192 orthologues and 80 paralogues. Biased expression in brain (RPKM 4.1) and adrenal (RPKM 0.2).
Summary
Predicted to enable zinc ion binding activity. Predicted to be involved in regulation of protein localization. Predicted to act upstream of or within negative regulation of Ras protein signal transduction; positive regulation of neuron projection development; and positive regulation of ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]
TRIM67 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001004342.5 | NP_001004342.3 | tripartite motif-containing protein 67 isoform 1 |
| NM_001300889.3 | NP_001287818.1 | tripartite motif-containing protein 67 isoform 2 |
| NM_001410937.1 | NP_001397866.1 | tripartite motif-containing protein 67 isoform 3 |
TRIM67 Protein Structure
zf-C3HC4: Zinc finger, C3HC4 type (RING finger) (7 - 35)
zf-B_box: B-box zinc finger (301 - 340)
fn3: Fibronectin type III domain (526 - 597)
SPRY: SPRY domain (649 - 767)
- 0
- 200
- 400
- 600
- 783 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tripartite motif-containing protein 67 |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | TRIM67 | MGD | MGI:3045323 |
| Macaca mulatta | TRIM67 | VGNC | VGNC:79915 |
| Canis familiaris | TRIM67 | VGNC | VGNC:47834 |
| Bos taurus | TRIM67 | VGNC | VGNC:55996 |
| Rattus norvegicus | TRIM67 | RGD | RGD:1560667 |
| Others | TRIM67 | NCBI |