Galns - galactosamine (N-acetyl)-6-sulfate sulfatase Gene

Also Known as mFLJ00319

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50917

Summary

Predicted to enable arylsulfatase activity. Predicted to be located in lysosome. Is expressed in embryo; lens epithelium; neural retina; and retina. Used to study mucopolysaccharidosis IV. Human ortholog(s) of this gene implicated in mucopolysaccharidosis IVA. Orthologous to human GALNS (galactosamine (N-acetyl)-6-sulfatase). [provided by Alliance of Genome Resources, Apr 2022]

Galns Products (2)

mRNA Protein Name
NM_001193645.1 NP_001180574.1 N-acetylgalactosamine-6-sulfatase isoform 2 precursor
NM_016722.4 NP_057931.3 N-acetylgalactosamine-6-sulfatase isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables N-acetylgalactosamine-6-sulfatase activity IMP
IMP: Inferred from mutant phenotype
14583446 MGI
Cellular Component GO Annotation Evidence References Source
is active in lysosome IMP
IMP: Inferred from mutant phenotype
17498992 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-acetylgalactosamine-6-sulfatase

  • GalNAc6S sulfatase

  • N-acetylgalactosamine-6-sulfate sulfatase

  • chondroitinase

  • chondroitinsulfatase

  • galactose-6-sulfate sulfatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N1441 Afzelin 99.62% Unkown
HY-122920 Soyasaponin II Inhibitor 99.81% Unkown
HY-D1633A 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium 99.92% Unkown
HY-D1633 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate 95.0% Unkown
HY-184736 STAT3/NF-κB-IN-3 Inhibitor / Unkown
HY-E70188 N-Acetylgalactosamine-6-Sulfatase / Unkown
HY-P10241 Ac-LEHD-CHO Inhibitor / Unkown
HY-RS05246 GALNS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N12069 Praeroside IV / Unkown
HY-RS20933 Galns Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27450 Galns Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Galns NCBI NCBI:2588