MBIP - MAP3K12 binding inhibitory protein 1 Gene

Homo sapiens

Gene ID: 51562 | Gene type: protein coding

About MBIP

Cytogenetic location: 14q13.3 Genomic coordinates (GRCh38): 14:36,298,564-36,320,637 (from NCBI)

This gene has 10 transcripts (splice variants), 197 orthologues and 3 paralogues. Broad expression in thyroid (RPKM 34.1), lung (RPKM 32.4) and 24 other tissues.

Summary

Enables identical protein binding activity and protein kinase inhibitor activity. Involved in histone H3 acetylation; positive regulation of JNK cascade; and positive regulation of gene expression. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MBIP Products(3)

mRNA	Protein	Name
NM_001144891.2	NP_001138363.1	MAP3K12-binding inhibitory protein 1 isoform 2
NM_001308110.2	NP_001295039.1	MAP3K12-binding inhibitory protein 1 isoform 3
NM_016586.3	NP_057670.2	MAP3K12-binding inhibitory protein 1 isoform 1

Protein Preferred Names

Protein Names

MAP3K12-binding inhibitory protein 1

MAPK upstream kinase-binding inhibitory protein

Recombinant MBIP Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70921	MBIP Protein, Human (His)	Q9NS73 (M1-P344)	≥95%

Related Diseases

Diseases

Alias

Bronchus Adenoma

Bronchial Adenoma

Adenoma Of The Bronchus

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08187	MBIP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MBIP	MGD	MGI:1918320
Bos taurus	MBIP	VGNC	VGNC:31279
Felis catus	MBIP	VGNC	VGNC:80921
Canis familiaris	MBIP	VGNC	VGNC:43055
Macaca mulatta	MBIP	VGNC	VGNC:74543
Rattus norvegicus	MBIP	RGD	RGD:1306310
Others	MBIP	NCBI