MDM2 - MDM2 proto-oncogene Gene

Species: Bos taurus

Gene Type: protein coding
Gene ID: 540378

About MDM2

Primary_assembly 5: 44,979,892-45,005,325 reverse strand.ARS-UCD1.2:CM008172.2

This gene has 5 transcripts (splice variants), 254 orthologues and 3 paralogues.

MDM2 Products (1)

mRNA Protein Name
NM_001099107.1 NP_001092577.1 E3 ubiquitin-protein ligase Mdm2

MDM2 Protein Structure

MDM2

MDM2: cd17672 (24 - 106)

zf-RanBP

zf-RanBP: pfam00641 (299 - 328)

mRING-HC-C2H2C4_MDM2

mRING-HC-C2H2C4_MDM2: cd16783 (435 - 491)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 492 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase Mdm2

  • MDM2-like protein

  • Mdm2 p53 binding protein homolog

  • Mdm2, p53 E3 ubiquitin protein ligase homolog

  • Mdm2, transformed 3T3 cell double minute 2, p53 binding protein

  • double minute 2 protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-N0004 Oridonin 99.89% Phase 4

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130684 MDM2 ligand 5 98.02% Unkown
HY-128837 Nutlin carboxylic acid 98.63% Unkown
HY-P5930 HOXB7 8–25 / Unkown
HY-128837A (rel)-Nutlin carboxylic acid / Unkown
HY-128836 (4R,5S)-Nutlin carboxylic acid / Unkown
HY-168280 AS1411-C4-VH032 Degrader / Unkown
HY-148106 MEL23 Inhibitor / Unkown
HY-181813 PROTAC DHFR Degrader-1 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MDM2 NCBI NCBI:4193