Arl6ip1 - ADP-ribosylation factor-like 6 interacting protein 1 Gene

Also Known as AIP-6; ARMER; Aip-1; Arl6ip; mKIAA0069

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54208

Summary

Predicted to enable identical protein binding activity. Involved in positive regulation of L-glutamate import across plasma membrane. Acts upstream of or within cotranslational protein targeting to membrane. Located in cytosol and endoplasmic reticulum. Is integral component of membrane. Part of Sec61 translocon complex. Is expressed in several structures, including central nervous system; genitourinary system; retina; and stomach. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 61. Orthologous to human ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Arl6ip1 Products (1)

mRNA Protein Name
NM_019419.2 NP_062292.1 ADP-ribosylation factor-like protein 6-interacting protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10508919 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cotranslational protein targeting to membrane IDA
IDA: Inferred from direct assay
10508919 MGI
involved in positive regulation of L-glutamate import across plasma membrane IDA
IDA: Inferred from direct assay
18684713 MGI
Cellular Component GO Annotation Evidence References Source
part of Sec61 translocon complex IDA
IDA: Inferred from direct assay
10508919 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
10995579 MGI
located in cytosol IDA
IDA: Inferred from direct assay
10508919 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
18684713 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
18684713 MGI
located in membrane IDA
IDA: Inferred from direct assay
10995579 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP-ribosylation factor-like protein 6-interacting protein 1

  • ADP-ribosylation-like factor 6 interacting protein

  • ARL-6-interacting protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00994 ARL6IP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21227 Arl6ip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27744 Arl6ip1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arl6ip1 NCBI NCBI:23204