2. Gene
  3. MS4A7 - membrane spanning 4-domains A7 Gene

MS4A7 - membrane spanning 4-domains A7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CFFM4; MS4A8; 4SPAN2; CD20L4

Gene ID: 58475 | Gene type: protein coding

About MS4A7

Cytogenetic location: 11q12.2 Genomic coordinates (GRCh38): 11:60,378,532-60,395,948 (from NCBI)

This gene has 12 transcripts (splice variants), 342 orthologues and 16 paralogues. Broad expression in spleen (RPKM 76.0), lung (RPKM 24.9) and 15 other tissues.

Summary

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

MS4A7 Products(4)

mRNA Protein Name
NM_021201.5 NP_067024.1 membrane-spanning 4-domains subfamily A member 7 isoform 1
NM_206938.2 NP_996821.1 membrane-spanning 4-domains subfamily A member 7 isoform 2
NM_206939.2 NP_996822.1 membrane-spanning 4-domains subfamily A member 7 isoform 1
NM_206940.2 NP_996823.1 membrane-spanning 4-domains subfamily A member 7 isoform 2

MS4A7 Protein Structure

CD20

CD20: CD20-like family (47 - 207)

  • 0
  • 100
  • 200
  • 240 a.a.
Protein Preferred Names Protein Names

membrane-spanning 4-domains subfamily A member 7

CD20 antigen-like 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08705 MS4A7 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MS4A7 VGNC VGNC:101363
Canis familiaris MS4A7 VGNC VGNC:49673
Rattus norvegicus MS4A7 RGD RGD:1305549
Mus musculus MS4A7 MGD MGI:1918846
Felis catus MS4A7 VGNC VGNC:63632