S1PR4 - sphingosine-1-phosphate receptor 4 Gene

Also Known as EDG6

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 612082

About S1PR4

Primary_assembly 20: 56,767,763-56,768,914 reverse strand.ROS_Cfam_1.0:CM025119.1

This gene has 1 transcript (splice variant), 176 orthologues and 16 paralogues.

S1PR4 Products (1)

mRNA Protein Name
XM_038429179.1 XP_038285107.1 sphingosine 1-phosphate receptor 4

S1PR4 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (47 - 318)

7tm_GPCRs

7tm_GPCRs: cd14964 (49 - 73)

7tm_GPCRs

7tm_GPCRs: cd14964 (82 - 103)

7tm_GPCRs

7tm_GPCRs: cd14964 (119 - 141)

7tm_GPCRs

7tm_GPCRs: cd14964 (164 - 180)

7tm_GPCRs

7tm_GPCRs: cd14964 (201 - 224)

7tm_GPCRs

7tm_GPCRs: cd14964 (250 - 272)

7tm_GPCRs

7tm_GPCRs: cd14964 (286 - 311)

  • 0
  • 100
  • 200
  • 300
  • 383 a.a.
Protein Preferred Names Protein Names

sphingosine 1-phosphate receptor 4

  • endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12355 Siponimod Agonist 99.95% Yes
HY-10569 Ponesimod Agonist 99.78% Yes
HY-12355A Siponimod hemifumarate Agonist 99.64% Yes

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-17606 Cenerimod Agonist 99.43% Phase 3

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-136462 CYM50358 Antagonist 98.33% Unkown
HY-111253 CYM-5478 Agonist 99.90% Unkown
HY-176533 S1PR5-IN-1 Inhibitor 99.58% Unkown
HY-116146 CYM50179 Agonist 96.06% Unkown
HY-W040167 VPC 23153 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S1PR4 NCBI NCBI:8698