1. GPCR/G Protein
  2. LPL Receptor
  3. CYM50179

CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC50 of 46 nM.

For research use only. We do not sell to patients.

CYM50179 Chemical Structure

CYM50179 Chemical Structure

CAS No. : 1355026-47-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 94 In-stock
Solution
10 mM * 1 mL in DMSO USD 94 In-stock
Solid
5 mg USD 85 In-stock
10 mg USD 145 In-stock
25 mg USD 300 In-stock
50 mg USD 510 Get quote
100 mg USD 860 Get quote
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC50 of 46 nM[1].

IC50 & Target[1]

S1PR4

46 nM (EC50)

Molecular Weight

441.93

Formula

C13H9Br2Cl2NO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC(Cl)=C(C=C1)OCCOC2=C(N=C(C=C2)Br)Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (141.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2628 mL 11.3140 mL 22.6280 mL
5 mM 0.4526 mL 2.2628 mL 4.5256 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2628 mL 11.3140 mL 22.6280 mL 56.5700 mL
5 mM 0.4526 mL 2.2628 mL 4.5256 mL 11.3140 mL
10 mM 0.2263 mL 1.1314 mL 2.2628 mL 5.6570 mL
15 mM 0.1509 mL 0.7543 mL 1.5085 mL 3.7713 mL
20 mM 0.1131 mL 0.5657 mL 1.1314 mL 2.8285 mL
25 mM 0.0905 mL 0.4526 mL 0.9051 mL 2.2628 mL
30 mM 0.0754 mL 0.3771 mL 0.7543 mL 1.8857 mL
40 mM 0.0566 mL 0.2829 mL 0.5657 mL 1.4143 mL
50 mM 0.0453 mL 0.2263 mL 0.4526 mL 1.1314 mL
60 mM 0.0377 mL 0.1886 mL 0.3771 mL 0.9428 mL
80 mM 0.0283 mL 0.1414 mL 0.2829 mL 0.7071 mL
100 mM 0.0226 mL 0.1131 mL 0.2263 mL 0.5657 mL
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CYM50179 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CYM50179
Cat. No.:
HY-116146
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