MMP27 - matrix metallopeptidase 27 Gene

Also Known as MMP-27

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64066

About MMP27

Cytogenetic location: 11q22.2 Genomic coordinates (GRCh38): 11:102,691,487-102,705,769 (from NCBI)

This gene has 1 transcript (splice variant), 441 orthologues and 23 paralogues. Low expression observed in reference dataset.

Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. [provided by RefSeq, Jul 2008]

MMP27 Products (1)

mRNA Protein Name
NM_022122.3 NP_071405.2 matrix metalloproteinase-27 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
24548619 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MMP27 Protein Structure

PG_binding_1

PG_binding_1: Putative peptidoglycan binding domain (27 - 86)

Peptidase_M10

Peptidase_M10: Matrixin (106 - 261)

Hemopexin

Hemopexin: Hemopexin (285 - 326)

Hemopexin

Hemopexin: Hemopexin (330 - 370)

Hemopexin

Hemopexin: Hemopexin (376 - 421)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 513 a.a.
Protein Preferred Names Protein Names

matrix metalloproteinase-27

  • matrix metalloprotease 27

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08546 MMP27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MMP27 VGNC VGNC:74749
Mus musculus MMP27 MGD MGI:3039232
Felis catus MMP27 VGNC VGNC:63538
Canis familiaris MMP27 VGNC VGNC:43286
Rattus norvegicus MMP27 RGD RGD:1306642
Bos taurus MMP27 VGNC VGNC:54886
Others MMP27 NCBI