Myo1c - myosin 1C Gene

Also Known as MMIb; Myr2; MMI-beta

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65261

Summary

Enables actin filament binding activity; Calmodulin binding activity; and microfilament motor activity. Involved in positive regulation of actin filament polymerization and positive regulation of cellular response to Insulin stimulus. Located in several cellular components, including membrane raft; ruffle membrane; and stereocilium bundle. Orthologous to human MYO1C (Myosin IC). [provided by Alliance of Genome Resources, Apr 2022]

Myo1c Products (2)

mRNA Protein Name
NM_001414168.1 NP_001401097.1 unconventional myosin-Ic isoform 1
NM_023092.3 NP_075580.2 unconventional myosin-Ic isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin filament binding IDA
IDA: Inferred from direct assay
15647165 RGD
enables calmodulin binding IDA
IDA: Inferred from direct assay
18729383 RGD
enables microfilament motor activity IDA
IDA: Inferred from direct assay
15647165 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of actin filament polymerization IMP
IMP: Inferred from mutant phenotype
22918957 RGD
involved in positive regulation of cellular response to insulin stimulus IMP
IMP: Inferred from mutant phenotype
22918957 RGD
Cellular Component GO Annotation Evidence References Source
located in membrane raft IDA
IDA: Inferred from direct assay
21402783 RGD
located in ruffle membrane IDA
IDA: Inferred from direct assay
22918957 RGD
located in stereocilium bundle IDA
IDA: Inferred from direct assay
12486594 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-Ic

  • myosin I beta

  • myosin IC

  • myosin IC-like

  • myosin heavy chain myr 2

  • myosin-Ic

  • unconventional myosin Myr2 I heavy chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08939 MYO1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08941 MYO1E Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21659 Myo1c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28177 Myo1c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo1c NCBI NCBI:4641