Rps6ka6 - ribosomal protein S6 kinase polypeptide 6 Gene
Also Known as RSK4; S6K-alpha-6; 2610524K04Rik
Species: Mus musculus
About Rps6ka6
This gene has 11 transcripts (splice variants), 207 orthologues, 7 paralogues and is associated with 9 phenotypes. Biased expression in placenta adult (RPKM 15.3), CNS E11.5 (RPKM 4.6) and 7 other tissues.
Summary
Predicted to enable ribosomal protein S6 kinase activity. Involved in negative regulation of ERK1 and ERK2 cascade; negative regulation of embryonic development; and negative regulation of mesoderm development. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in several structures, including genitourinary system; nervous system; nose; respiratory system; and thymus primordium. Orthologous to human RPS6KA6 (ribosomal protein S6 kinase A6). [provided by Alliance of Genome Resources, Apr 2022]
Rps6ka6 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001398774.1 | NP_001385703.1 | ribosomal protein S6 kinase alpha-6 isoform 2 |
| NM_001374707.3 | NP_001361636.2 | ribosomal protein S6 kinase alpha-6 isoform 2 |
| NM_025949.3 | NP_080225.2 | ribosomal protein S6 kinase alpha-6 isoform 1 |
Rps6ka6 Protein Structure
STKc_RSK_N: cd05582 (192 - 506)
STKc_RSK_C: cd14091 (541 - 827)
- 0
- 200
- 400
- 600
- 800
- 860 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ribosomal protein S6 kinase alpha-6 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS12259 | RPS6KA6 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS12260 | Rps6ka6 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS12261 | Rps6ka6 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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