Cert1 - ceramide transporter 1 Gene

Also Known as CERT; GPBP; Col4a3bp; 2810404O15Rik; 9230101K08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68018

Summary

Enables kinase activity. Involved in ER to Golgi ceramide transport. Acts upstream of or within several processes, including ceramide metabolic process; lipid homeostasis; and mitochondrion morphogenesis. Located in cytosol and mitochondrion. Is expressed in several structures, including alimentary system; eye; nervous system; respiratory system; and urinary system. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 34. Orthologous to human CERT1 (ceramide transporter 1). [provided by Alliance of Genome Resources, Apr 2022]

Cert1 Products (2)

mRNA Protein Name
NM_001164222.1 NP_001157694.1 ceramide transfer protein isoform 2
NM_023420.2 NP_075909.1 ceramide transfer protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables kinase activity IDA
IDA: Inferred from direct assay
11007769 MGI
Biological Process GO Annotation Evidence References Source
involved in ER to Golgi ceramide transport IMP
IMP: Inferred from mutant phenotype
24642596 MGI
acts upstream of or within cell morphogenesis IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within cell population proliferation IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within ceramide metabolic process IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within endoplasmic reticulum organization IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within heart morphogenesis IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within lipid homeostasis IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within mitochondrion organization IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within muscle contraction IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
19139267 MGI
acts upstream of or within signal transduction IMP
IMP: Inferred from mutant phenotype
19139267 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
19139267 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
19139267 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ceramide transfer protein

  • START domain-containing protein 11

  • ceramide transport protein

  • collagen type IV alpha-3-binding protein

  • collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

  • goodpasture antigen-binding protein

  • procollagen, type IV, alpha 3 (Goodpasture ant

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02542 CERT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20882 Cert1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27399 Cert1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cert1 NCBI NCBI:10087