Nrn1 - neuritin 1 Gene

Also Known as Nrn; Cpg15; 0710008J23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68404

Summary

Enables identical protein binding activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within neuron projection extension. Located in extracellular space. Is anchored component of plasma membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb mesenchyme; and liver. Orthologous to human NRN1 (neuritin 1). [provided by Alliance of Genome Resources, Apr 2022]

Nrn1 Products (2)

mRNA Protein Name
NM_001374754.1 NP_001361683.1 neuritin isoform 2
NM_153529.2 NP_705757.1 neuritin isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
18265009 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18265009 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within neuron projection extension IDA
IDA: Inferred from direct assay
18265009 MGI
involved in presynaptic modulation of chemical synaptic transmission EXP
EXP: Inferred from Experiment
28475719 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
28475719 MGI
involved in presynaptic modulation of chemical synaptic transmission IEP
IEP: Inferred from expression pattern
28475719 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
28475719 MGI
involved in regulation of synapse maturation IDA
IDA: Inferred from direct assay
22190461 MGI
involved in regulation of synapse maturation IMP
IMP: Inferred from mutant phenotype
22190461 MGI
Cellular Component GO Annotation Evidence References Source
part of AMPA glutamate receptor complex IDA
IDA: Inferred from direct assay
22632720 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
18265009 MGI
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
28475719 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
28475719 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
28475719 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
28475719 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
18265009 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuritin

  • candidate plasticity gene 15 protein

  • candidate plasticity-related gene 15

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09577 NRN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09578 NRN1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18253 Nrn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20070 Nrn1l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24733 Nrn1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26574 Nrn1l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrn1 NCBI NCBI:51299