SLC25A16 - solute carrier family 25 member 16 Gene
Also Known as GDA; GDC; ML7; hML7; HGT.1; D10S105E
Species: Homo sapiens
About SLC25A16
This gene has 7 transcripts (splice variants), 196 orthologues and 49 paralogues. Ubiquitous expression in fat (RPKM 11.2), prostate (RPKM 5.7) and 25 other tissues.
Summary
This gene encodes a protein that contains three tandemly repeated mitochondrial carrier protein domains. The encoded protein is localized in the inner membrane and facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space. This gene has a possible role in Graves' disease. [provided by RefSeq, Jul 2008]
SLC25A16 Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001324312.2 | NP_001311241.1 | solute carrier family 25 member 16 isoform b |
| NM_001324313.2 | NP_001311242.1 | solute carrier family 25 member 16 isoform c |
| NM_001324314.2 | NP_001311243.1 | solute carrier family 25 member 16 isoform d |
| NM_001324315.1 | NP_001311244.1 | solute carrier family 25 member 16 isoform d |
| NM_001324317.2 | NP_001311246.1 | solute carrier family 25 member 16 isoform e |
| NM_152707.4 | NP_689920.1 | solute carrier family 25 member 16 isoform a |
SLC25A16 Protein Structure
Mito_carr: Mitochondrial carrier protein (34 - 124)
Mito_carr: Mitochondrial carrier protein (130 - 216)
Mito_carr: Mitochondrial carrier protein (240 - 330)
- 0
- 100
- 200
- 300
- 332 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
solute carrier family 25 member 16 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Isolated Nail Anomaly |
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| Nonsyndromic Congenital Nail Disorder |
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| Graves' Disease |
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| Endocervical Carcinoma |
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| Uterine Body Mixed Cancer |
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| Uterine Corpus Cancer |
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| Ovarian Cystadenocarcinoma |
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| Endocervical Adenocarcinoma |
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| Rectum Adenocarcinoma |
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| Chromophobe Renal Cell Carcinoma |
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| Uterine Carcinosarcoma |
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| Brain Glioma |
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| Ovarian Serous Cystadenocarcinoma |
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| Phenylketonuria |
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| Suppression Of Tumorigenicity 12 |
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| Ovary Adenocarcinoma |
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| Cervix Carcinoma |
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| Esophageal Cancer |
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| Ichthyosis, Congenital, Autosomal Recessive 3 |
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| Renal Cell Carcinoma, Nonpapillary |
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| Adrenal Cortical Carcinoma |
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| Melanoma, Uveal |
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| Renal Cell Carcinoma, Papillary, 1 |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | SLC25A16 | VGNC | VGNC:77433 |
| Felis catus | SLC25A16 | VGNC | VGNC:65258 |
| Canis familiaris | SLC25A16 | VGNC | VGNC:46295 |
| Bos taurus | SLC25A16 | VGNC | VGNC:55993 |
| Mus musculus | SLC25A16 | MGD | MGI:1920382 |
| Rattus norvegicus | SLC25A16 | RGD | RGD:1311311 |
| Others | SLC25A16 | NCBI |