SLC25A16 - solute carrier family 25 member 16 Gene

Also Known as GDA; GDC; ML7; hML7; HGT.1; D10S105E

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8034

About SLC25A16

Cytogenetic location: 10q21.3 Genomic coordinates (GRCh38): 10:68,477,998-68,527,523 (from NCBI)

This gene has 7 transcripts (splice variants), 196 orthologues and 49 paralogues. Ubiquitous expression in fat (RPKM 11.2), prostate (RPKM 5.7) and 25 other tissues.

Summary

This gene encodes a protein that contains three tandemly repeated mitochondrial carrier protein domains. The encoded protein is localized in the inner membrane and facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space. This gene has a possible role in Graves' disease. [provided by RefSeq, Jul 2008]

SLC25A16 Products (6)

mRNA Protein Name
NM_001324312.2 NP_001311241.1 solute carrier family 25 member 16 isoform b
NM_001324313.2 NP_001311242.1 solute carrier family 25 member 16 isoform c
NM_001324314.2 NP_001311243.1 solute carrier family 25 member 16 isoform d
NM_001324315.1 NP_001311244.1 solute carrier family 25 member 16 isoform d
NM_001324317.2 NP_001311246.1 solute carrier family 25 member 16 isoform e
NM_152707.4 NP_689920.1 solute carrier family 25 member 16 isoform a

SLC25A16 Protein Structure

Mito_carr

Mito_carr: Mitochondrial carrier protein (34 - 124)

Mito_carr

Mito_carr: Mitochondrial carrier protein (130 - 216)

Mito_carr

Mito_carr: Mitochondrial carrier protein (240 - 330)

  • 0
  • 100
  • 200
  • 300
  • 332 a.a.
Protein Preferred Names Protein Names

solute carrier family 25 member 16

  • graves disease carrier protein

Related Diseases

Diseases Alias
Isolated Nail Anomaly
Nonsyndromic Congenital Nail Disorder
  • Nail Disorder, Nonsyndromic Congenital

Graves' Disease
  • Graves Disease

  • Exophthalmic Goiter

  • Basedow'S Disease

  • Grave'S Disease

  • Basedow Disease

  • Toxic Diffuse Goiter

  • Graves' Hyperthyroidism

  • Parry Disease

  • Autoimmune Hyperthyroidism

  • Toxic Multinodular Goiter

Endocervical Carcinoma
  • Carcinoma Of Endocervix

  • Carcinoma Of The Endocervix

Uterine Body Mixed Cancer
  • Malignant Mixed Tumor Of Corpus Uteri

  • Malignant Mixed Tumor, Not Otherwise Specified

Uterine Corpus Cancer
  • Corpus Uteri Cancer

  • Malignant Uterine Corpus Neoplasm

Ovarian Cystadenocarcinoma
  • Cystadenocarcinoma Of Ovary

  • Cystadenocarcinoma Of The Ovary

Endocervical Adenocarcinoma
  • Endocervical Carcinoma

Rectum Adenocarcinoma
  • Rectal Adenocarcinoma

  • Adenocarcinoma Of Rectum

Chromophobe Renal Cell Carcinoma
  • Chromophobe Adenocarcinoma

  • Chromophobe Carcinoma Of Kidney

  • Kidney Chromophobe

  • Renal Cell Carcinoma, Chromophobe Cell

  • Crcc

  • Chrcc

  • Chromophobe Renal Cell Adenocarcinoma

  • Chromophobe Renal Carcinoma

  • Chromophobe Carcinoma

Uterine Carcinosarcoma
  • Carcinosarcoma Of The Corpus Uteri

  • Mixed Mullerian Sarcoma Of Uterus

  • Malignant Mixed Müllerian Tumor Of The Corpus Uteri

  • Malignant Mixed Müllerian Tumor Of Corpus Uteri

  • Mixed Müllerian Cancer Of Corpus Uteri

  • Malignant Mixed Mullerian Tumor Of The Corpus Uteri

  • Mixed Mullerian Cancer Of Corpus Uteri

  • Uterine Corpus Carcinosarcoma

Brain Glioma
  • Lower Grade Glioma

  • Intracranial Glioma

  • Glioma Nos

Ovarian Serous Cystadenocarcinoma
  • Serous Cystadenoma

  • Cystadenoma Serous

  • Cystadenoma, Serous

Phenylketonuria
  • Phenylalanine Hydroxylase Deficiency

  • PKU

  • Pah Deficiency

  • Folling Disease

  • Maternal Phenylketonuria

  • Phenylketonurias

  • Oligophrenia Phenylpyruvica

  • Hyperphenylalaninemia, Non-Pku Mild

  • Folling'S Disease

  • Phenylalaninemia

  • Mild Phenylketonuria

  • Mild Pku

  • Variant Pku

  • Variant Phenylketonuria

  • Mpku

  • Deficiency Disease, Phenylalanine Hydroxylase

  • Phenylketonuria, Maternal

  • Phenylalanine Hydroxylase Deficiency Disease

  • Hyperphenylalaninemic Embryopathy

  • Maternal Pku

  • Maternal Hyperphenylalaninemia

  • Phenylketonuric Embryopathy

  • Hyperphenylalaninemia

  • HPA

  • Non-Phenylketonuria Hyperphenylalaninemia

  • NON-PKU HPA

  • Phenylketonuria Maternal

  • Classical Phenylketonuria

  • Hyperphenylalaninaemia

  • Pku - [Phenylketonuria]

Suppression Of Tumorigenicity 12
  • Prostate Adenocarcinoma

  • Adenocarcinoma Of Prostate

  • ST12

  • Prostate Adenocarcinoma 1

  • Pac1

Ovary Adenocarcinoma
  • Ovarian Adenocarcinoma

  • Adenocarcinoma Of The Ovary

  • Ovarian Adenoacanthoma

  • Adenocarcinoma Of Ovary

Cervix Carcinoma
  • Cancer Of Cervix

  • Carcinoma Of Cervix

  • Carcinoma Cervix Uteri

  • Carcinoma Of The Cervix Uteri

Esophageal Cancer
  • Esophageal Carcinoma

  • Carcinoma Of Esophagus

  • Esophageal Squamous Cell Carcinoma, Somatic

  • Esophageal Carcinoma, Somatic

  • Esophagus Cancer

  • Gastric Cardia Adenocarcinoma

  • Esophageal Neoplasms

  • Esophageal Cancer, Somatic

  • Cancer Of Esophagus

  • Cancer Of Oesophagus

  • Carcinoma Of Oesophagus

  • Ca Lower Third Oesophagus

  • Ca Middle Third Oesophagus

  • Malignant Neoplasm Of Distal Third Of Esophagus

  • Malignant Neoplasm Of Lower Third Of Oesophagus

  • Malignant Neoplasm Of Middle Third Of Oesophagus

  • Malignant Neoplasm Of Proximal Third Of Esophagus

  • Malignant Neoplasm Of Upper Third Esophagus

  • Malignant Tumor Of Abdominal Esophagus

  • Malignant Tumor Of Distal Third Of Esophagus

  • Malignant Tumor Of Proximal Third Of Esophagus

  • Malignant Tumor Of The Middle Third Of The Esophagus

  • ESCR

  • Aerodigestive Tract Cancer

  • Escc

  • Esophageal Squamous Cell Carcinoma

  • Cancer, Esophageal

  • Malignant Neoplasm Of Esophagus

  • Squamous Cell Carcinoma Of Esophagus

  • Malignant Neoplasm Of Middle Third Of Esophagus

Ichthyosis, Congenital, Autosomal Recessive 3
  • Autosomal Recessive Congenital Ichthyosis 3

  • ARCI3

  • Lamellar Ichthyosis 5

  • Collodion Baby, Self-Healing

  • Ichthyosis, Lamellar, 5, Formerly

  • Li5, Formerly

  • Li5

  • Self-Healing Collodion Baby

  • Ichthyosis, Congenital, Autosomal Recessive, Type 3

Renal Cell Carcinoma, Nonpapillary
  • Renal Cell Carcinoma

  • RCC

  • Nonpapillary Renal Cell Carcinoma

  • Clear Cell Renal Cell Carcinoma

  • Hypernephroma

  • Adenocarcinoma Of Kidney

  • Renal Carcinoma, Chromophobe, Somatic

  • Clear Cell Carcinoma Of Kidney

  • Clear-Cell Metastatic Renal Cell Carcinoma

  • Clear Cell Renal Carcinoma

  • Renal Cell Carcinoma, Somatic

  • Conventional Renal Cell Carcinoma

  • Conventional Renal Cell Carcinoma

  • Renal Clear Cell Carcinoma

  • Ccrcc

  • Hereditary Clear Cell Renal Cell Carcinoma

  • Carcinoma, Renal Cell

  • Renal Cell Carcinoma, Clear Cell, Somatic

  • Renal Cell Carcinoma, Clear Cell

  • Clear Cell Kidney Carcinoma

  • Clear Cell Rcc

  • Cystic-Multilocular Variant

  • Clear Cell Renal Cell Adenocarcinoma

  • Hereditary Clear Cell Renal Cell Adenocarcinoma

  • Common Renal Cell Carcinoma

  • Crcc

  • Renal Cell Carcinoma Non-Papillary

  • Carcinoma Renal Cell

  • Renal Cell Cancer

  • Carcinoma, Renal Cell, Nonpapillary

Adrenal Cortical Carcinoma
  • Adrenocortical Carcinoma

  • Adrenal Cortex Carcinoma

  • Carcinoma Of The Adrenal Cortex

  • Acc

  • Adrenocortical Cancer

  • Carcinoma Adrenocortical

Melanoma, Uveal
  • Uveal Melanoma

  • Choroidal Melanoma

  • Melanoma Of Uvea

  • Iris Melanoma

  • Malignant Melanoma Of Choroid

  • Malignant Melanoma Of Iris

Renal Cell Carcinoma, Papillary, 1
  • Papillary Renal Cell Carcinoma

  • Hereditary Papillary Renal Cell Carcinoma

  • Papillary Renal Cell Carcinoma, Sporadic

  • Papillary Renal Cell Adenocarcinoma

  • RCCP

  • RCCP1

  • Renal Cell Carcinoma, Papillary

  • Renal Cell Carcinoma, Papillary, 1, Familial And Somatic

  • Chromophil Carcinoma Of Kidney

  • Papillary Kidney Carcinoma

  • Sporadic Papillary Renal Cell Carcinoma

  • Chromophil Renal Cell Carcinoma

  • Papillary Renal Carcinoma, Malignant -

  • Papillary Renal Cell Carcinoma, Bilateral -

  • Papillary Renal Cell Carcinoma, Familial -

  • Papillary Renal Cell Carcinoma, Multiple -

  • Papillary Renal Cell Carcinoma, Sporadic -

  • Renal Adenocarcinoma

  • Chromophil Rcc

  • Hprcc

  • Renal Cell Carcinoma Papillary

  • Chromophilic Renal Cell Carcinoma

  • Prcc

  • Carcinoma, Renal Cell, Papillary, Type 1

  • Type 1 Papillary Renal Cell Carcinoma

  • Renal Cell Carcinoma

  • Hereditary Papillary Renal Carcinoma

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLC25A16 VGNC VGNC:77433
Felis catus SLC25A16 VGNC VGNC:65258
Canis familiaris SLC25A16 VGNC VGNC:46295
Bos taurus SLC25A16 VGNC VGNC:55993
Mus musculus SLC25A16 MGD MGI:1920382
Rattus norvegicus SLC25A16 RGD RGD:1311311
Others SLC25A16 NCBI