Aldh6a1 - aldehyde dehydrogenase 6 family, member A1 Gene

Also Known as Mmsdh

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81708

Summary

Enables malonate-semialdehyde dehydrogenase (acetylating) activity; methylmalonate-semialdehyde dehydrogenase (acylating) activity; and thiolester hydrolase activity. Involved in beta-alanine catabolic process; thymine catabolic process; and valine catabolic process. Predicted to be located in nucleoplasm. Predicted to be active in mitochondrion. Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1). [provided by Alliance of Genome Resources, Apr 2022]

Aldh6a1 Products (1)

mRNA Protein Name
NM_031057.2 NP_112319.2 methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity IDA
IDA: Inferred from direct assay
2768248 RGD
enables thiolester hydrolase activity IDA
IDA: Inferred from direct assay
1540637 RGD
Biological Process GO Annotation Evidence References Source
involved in beta-alanine catabolic process IDA
IDA: Inferred from direct assay
2768248 RGD
involved in thymine catabolic process IDA
IDA: Inferred from direct assay
2768248 RGD
involved in thymine metabolic process IDA
IDA: Inferred from direct assay
2768248 RGD
involved in valine catabolic process IDA
IDA: Inferred from direct assay
2768248 RGD
involved in valine metabolic process IDA
IDA: Inferred from direct assay
2768248 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial

  • aldehyde dehydrogenase family 6 member A1

  • aldehyde dehydrogenase family 6, subfamily A1

  • malonate-semialdehyde dehydrogenase

  • methylmalonate semialdehyde dehydrogenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00579 ALDH6A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28500 Aldh6a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aldh6a1 NCBI NCBI:4329