SPATA16 - spermatogenesis associated 16 Gene

Also Known as SPGF6; NYD-SP12

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 83893

About SPATA16

Cytogenetic location: 3q26.31 Genomic coordinates (GRCh38): 3:172,889,357-173,141,235 (from NCBI)

This gene has 2 transcripts (splice variants), 156 orthologues, 18 paralogues and is associated with 2 phenotypes. Restricted expression toward testis (RPKM 29.2).

Summary

This gene encodes a testis-specific protein that belongs to the tetratricopeptide repeat-like superfamily. The encoded protein localizes to the Golgi apparatus and may play a role in spermatogenesis. [provided by RefSeq, May 2010]

SPATA16 Products (1)

mRNA	Protein	Name
NM_031955.6	NP_114161.3	spermatogenesis-associated protein 16

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Verweise	Source
located in Golgi apparatus	IDA IDA: Inferred from direct assay	12529416	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SPATA16 Protein Structure

NYD-SP12_N

0
100
200
300
400
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569 a.a.

Protein Preferred Names	Protein Names
spermatogenesis-associated protein 16	testicular tissue protein Li 185

Related Diseases

Diseases	Alias
Spermatogenic Failure 6	Globozoospermia SPGF6 Round-Headed Spermatozoa Acrosome Malformation Of Spermatozoa Spermatogenic Failure 9 Spermatozoa, Round-Headed Globozoospermia, Complete Globozoospermia, Total Mae Infertility Due To Round-Headed Spermatozoa Male Infertility Due To Globozoospermia Male Infertility Due To Round-Headed Spermatozoa Round-Headed Sperm Syndrome Spgf9 Teratozoospermia
Spermatogenic Failure 9	Male Infertility Due To Globozoospermia SPGF9 Male Infertility Due To Round-Headed Spermatozoa Globozoospermia, Complete Globozoospermia, Total Globozoospermia Globozoospermia Syndrome Round-Headed Sperm Syndrome Globozoospermia Complete Globozoospermia Total
Oligospermia
Spermatogenic Failure	Azoospermia Spgf Spermatogenic Failure, Susceptibility To Absent Sperm Aspermatogenesis Infertility Due To Azoospermia Hypospermatogenesis Azoospermatism
Infertility
Oligoasthenoteratozoospermia	Oat Oligoasthenoteratospermia
Vas Deferens, Congenital Bilateral Aplasia Of	Congenital Bilateral Absence Of Vas Deferens CBAVD Cavd Congenital Bilateral Aplasia Of Vas Deferens Congenital Bilateral Absence Of The Vas Deferens Congenital Bilateral Agenesis Of Vas Deferens Absence Of Vas Deferens Absent Vasa Congenital Absence Of Vas Deferens Congenital Aplasia Of Vas Deferens Absent Vas Deferens Vas Deferens, Congenital Bilateral Absence
Spermatogenic Failure 5	Male Infertility With Large-Headed, Multiflagellar, Polyploid Spermatozoa Infertility Associated With Multi-Tailed Spermatozoa And Excessive Dna SPGF5 Macrocephalic Sperm Head Syndrome Male Infertility Due To Macrozoospermia Infertility Associated With Multitailed Spermatozoa And Excessive Dna Macrozoospermia Male Infertility Due To Large-Headed Multiflagellar Polyploid Spermatozoa Infertility Associated With Multi-Tailed Spermatozoa And Excessive Deoxyribonucleic Acid Large-Headed Multiflagellar Polyploid Spermatozoa Male Infertility With Large-Headed Multiflagellar Polyploid Spermatozoa
Spermatogenic Failure, X-Linked, 1	Sertoli Cell-Only Syndrome Germinal Cell Aplasia Del Castillo Syndrome SPGFX1 X-Linked Spermatogenic Failure 1 Congenital Absence Of Germinal Epithelium Of Testes
Warburg Micro Syndrome 1	Warburg Micro Syndrome Micro Syndrome Warbm WARBM1 Warburg Sjo Fledelius Syndrome Warburg-Sjo-Fledelius Syndrome Micro Syndrome 1 Microcephaly, Microcornea, Congenital Cataract, Intellectual Disability, Optic Atrophy And Hypogenitalism
Male Infertility	Infertility, Male Infertility Male Male Sterility Absolute Infertility
Premature Menopause	Primary Ovarian Insufficiency Premature Ovarian Failure Hypergonadotropic Hypogonadism Premature Ovarian Insufficiency Menopause - Premature Menopause Praecox Menopause Premature Menopause, Premature Female Hypergonadotropic Hypogonadism Hypergonadotrophic Ovarian Failure Primary Female Hypogonadism Pof - [Premature Ovarian Failure] Ovarian Failure Ovarian Secretion Suppression Ovary Hyposecretion Ovary Secretion Deficiency Premature Menopause Nos
Primary Ciliary Dyskinesia	Immotile Cilia Syndrome Kartagener Syndrome Dextrocardia Bronchiectasis And Sinusitis Pcd Ciliary Motility Disorders Ciliary Motility Disorder Immotile Ciliary Syndrome Ciliary Dyskinesia Primary Ics Polynesian Bronchiectasis Dextrocardia-Bronchiectasis-Sinusitis Syndrome Immotile Cilia Syndrome, Kartagener Type Primary Ciliary Dyskinesia And Situs Inversus Primary Ciliary Dyskinesia, Kartagener Type Siewert Syndrome Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-RS13637	SPATA16 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SPATA16	VGNC	VGNC:65604
Mus musculus	SPATA16	MGD	MGI:1918112
Canis familiaris	SPATA16	VGNC	VGNC:46704
Macaca mulatta	SPATA16	VGNC	VGNC:84073
Bos taurus	SPATA16	VGNC	VGNC:35175
Rattus norvegicus	SPATA16	RGD	RGD:1563726
Others	SPATA16	NCBI