SERPINB11 - serpin family B member 11 Gene

Homo sapiens

Also known as EPIPIN; SERPIN11

Gene ID: 89778 | Gene type: protein coding

About SERPINB11

Cytogenetic location: 18q21.33 Genomic coordinates (GRCh38): 18:63,702,304-63,723,893 (from NCBI)

This gene has 9 transcripts (splice variants), 115 orthologues and 36 paralogues. Biased expression in prostate (RPKM 17.6), esophagus (RPKM 11.7) and 1 other tissue.

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

SERPINB11 Products(4)

mRNA	Protein	Name
NM_001291278.2	NP_001278207.1	serpin B11 isoform b
NM_001291279.2	NP_001278208.1	serpin B11 isoform c
NM_001370475.1	NP_001357404.1	serpin B11 isoform a
NM_080475.5	NP_536723.2	serpin B11 isoform a

SERPINB11 Protein Structure

Serpin

0
100
200
300
392 a.a.

Protein Preferred Names

Protein Names

serpin B11

serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 11

Related Diseases

Diseases

Alias

Ovarian Endometrial Cancer

Endometrioid Neoplasm Of Ovary	Malignant Ovarian Endometrioid Tumor
Ovarian Endometrioid Neoplasm

Osteogenesis Imperfecta, Type Vi

OI6	Osteogenesis Imperfecta Type 6
Osteogenesis Imperfecta Type Vi	Oi Type Vi
Oi Type 6	Osteogenesis Imperfecta Type
Serpinfi- Related Osteogenesis Imperfecta	Osteogenesis Imperfecta 6
Oi-Vi

Endometrioid Ovary Carcinoma

Endometrioid Carcinoma Of Ovary	Endometrioid Carcinoma Ovary
Ovarian Endometrioid Carcinoma	Malignant Ovarian Endometrioid Tumor
Ovarian Endometrioid Tumor

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12707	SERPINB11 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SERPINB11	VGNC	VGNC:53529
Macaca mulatta	SERPINB11	VGNC	VGNC:99747
Rattus norvegicus	SERPINB11	RGD	RGD:1306497
Mus musculus	SERPINB11	MGD	MGI:1914207
Felis catus	SERPINB11	VGNC	VGNC:80484

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