GGGDTDTC-Mc-vc-PAB-MMAE
Based on 1 Customer Validation
GGGDTDTC-Mc-vc-PAB-MMAE is a Drug-Linker Conjugate for ADC, containing a tubulin inhibitor Monomethyl auristatin E (MMAE, HY-15162).
For research use only. We do not sell to patients.
- Purity : 99.75%
- Formula: C93H146N20O29S
- Molecular Weight:2040.34
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 2040.34
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Formula C93H146N20O29S
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Color White to off-white
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SMILES
CC([C@H](NC(CCCCCN1C(CC(C1=O)SC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC(CN)=O)=O)=O)CC(O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)[C@@H](C)O)=O)C(N)=O)=O)=O)C(N[C@H](C(NC2=CC=C(COC(N([C@H](C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N3CCC[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C4=CC=CC=C4)=O)3[H])=O)C)=O)=O)C(C)C)C)=O)C=C2)=O)CCCNC(N)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 200 mg/mL (98.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.4901 mL | 2.4506 mL | 4.9011 mL | 12.2529 mL |
| 5 mM | 0.0980 mL | 0.4901 mL | 0.9802 mL | 2.4506 mL | |
| 10 mM | 0.0490 mL | 0.2451 mL | 0.4901 mL | 1.2253 mL | |
| 15 mM | 0.0327 mL | 0.1634 mL | 0.3267 mL | 0.8169 mL | |
| 20 mM | 0.0245 mL | 0.1225 mL | 0.2451 mL | 0.6126 mL | |
| 25 mM | 0.0196 mL | 0.0980 mL | 0.1960 mL | 0.4901 mL | |
| 30 mM | 0.0163 mL | 0.0817 mL | 0.1634 mL | 0.4084 mL | |
| 40 mM | 0.0123 mL | 0.0613 mL | 0.1225 mL | 0.3063 mL | |
| 50 mM | 0.0098 mL | 0.0490 mL | 0.0980 mL | 0.2451 mL | |
| 60 mM | 0.0082 mL | 0.0408 mL | 0.0817 mL | 0.2042 mL | |
| 80 mM | 0.0061 mL | 0.0306 mL | 0.0613 mL | 0.1532 mL |
GGGDTDTC-Mc-vc-PAB-MMAE Related Classifications
HY-153428 Related Classifications
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