Glyceraldehyde-3-phosphate Dehydrogenase, Human

Glycerol-3-phosphate dehydrogenase, Human (GPDH; α-Glycerophosphate dehydrogenase; Glycerol phosphate dehydrogenase) is an NADH-dependent oxidoreductase derived from Human that participates in glycolysis, gluconeogenesis, and the glycerol‑3‑phosphate shuttle metabolic pathway. Glycerol-3-phosphate dehydrogenase, Human uses NADH as a reducing equivalent donor, and its substrate binding relies on the phosphate-binding site in the active center; it catalyzes the reversible reduction of dihydroxyacetone phosphate to L‑α‑glycerol‑3‑phosphate. The catalytic activity of the enzymatic reaction of Glycerol-3-phosphate dehydrogenase, Human is regulated by pH and divalent metal ions. Glycerol-3-phosphate dehydrogenase, Human can be used in metabolism-related studies.

• Data Sheet (270 KB)