GR 89696 free base
GR 89696 free base is a highly selective κ2 opioid receptor agonist with potential to prevent pruritus.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 126766-31-2
- 分子式: C19H25Cl2N3O3
- 分子量:414.33
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Opioid Receptor アイソフォーム固有の製品をすべて表示
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生物活性
GR-896960 free base (subcutaneous injection, 1 mg/kg) reduces cerebral artery infarct volume by 38% in a rat model of permanent focal ischemia[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 126766-31-2
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分子量 414.33
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分子式 C19H25Cl2N3O3
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SMILES
O=C(N1CCN(C(CN2CCCC2)C1)C(CC3=CC=C(C(Cl)=C3)Cl)=O)OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Mei-Chuan Ko, et al. Effects of atypical kappa-opioid receptor agonists on intrathecal morphine-induced itch and analgesia in primates. J Pharmacol Exp Ther. 2009 Jan;328(1):193-200. [Content Brief]
[2]. A Barber, et al. Effects of GR-89696 and the novel peripherally selective OP2 agonists, EMD-61569 and EMD-61747, against focal cerebral ischemia in the rat. Methods Find Exp Clin Pharmacol. 1999 Mar;21(2):105-13 [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
GR 89696 free base 関連分類
HY-107747A 関連分類
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