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Cat. No.: HY-170969

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HIV-1 inhibitor-81

HIV-1 inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a K_i of 1.6 nM. HIV-1 inhibitor-81 exhibits certain antiviral activity, with an EC₅₀ of 250 nM for HIV-1.

For research use only. We do not sell to patients.

Formula: C₃₂H₄₄N₂O₈S
Molecular Weight:616.77

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

HIV-1 inhibitor-81 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

HIV-1 inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a K_i of 1.6 nM. HIV-1 inhibitor-81 exhibits certain antiviral activity, with an EC₅₀ of 250 nM for HIV-1^[1].

All HIV Isoforms :

Chemical Information

Molecular Weight 616.77
Formula C₃₂H₄₄N₂O₈S
SMILES

[H][C@@]12C[C@H](O3)CC[C@H](OC(N[C@H]([C@H](O)CN(CC(C)C)S(C4=CC=C(OC)C=C4)(=O)=O)CC5=CC=CC=C5)=O)[C@@]13[C@H](C)OC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ghosh AK, et al. Potent HIV‑1 protease inhibitors containing oxabicyclo octanol-derived P2-ligands: Design, synthesis, and X‑ray structural studies of inhibitor-HIV-1 protease complexes. Bioorg Med Chem Lett. 2025 Jan 21;120:130109. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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HIV-1 inhibitor-81

All HIV Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

HIV-1 inhibitor-81 Related Classifications

HY-170969 Related Classifications

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Keywords

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