Euptox A
Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells.
For research use only. We do not sell to patients.
- CAS No.: 79491-71-7
- Formula: C15H20O2
- Molecular Weight:232.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Euptox A (0-2 μg/mL, 48 h) effectively inhibits the proliferation of HeLa cells[1].
Euptox A (0-50 μg/mL, 24 h) arrests the cell cycle transition from S to G2/M phase[1].
Euptox A presents significantly antitumor activity against the human lung cancer A549, HeLa and Hep-2 cell lines in vitro in a dose-dependent manner[1].
Euptox A exhibits highly acaricidal activity for S.scabiei and P. cuniculi in vitro[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 79491-71-7
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Molecular Weight 232.32
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Formula C15H20O2
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SMILES
C/C(C)=C1[C@@]2([H])[C@@](CC(C(C)=C2)=O)([H])[C@@H](C)CC/1=O
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Synonyms
9-Oxo-10,11-dehydroageraphorone
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)