Breast Cancer Models
N-Nitroso-N-methylurea
- Formula: C2H5N3O2
- Molecular Weight: 103.08
N-Nitroso-N-methylurea (NMU;MNU;NMH) is a potent carcinogen, mutagen and teratogenand. N-Nitroso-N-methylurea is a direct-acting alkylating agent that interacts with DNA. N-Nitroso-N-methylurea targets multiple animal organs to cause various cancer and/or degenerative disease. N-Nitroso-N-methylurea is also a precursor in the synthesis of diazomethane.
DMBA
Synonyms: 7,12-DMBA; 7,12-Dimethylbenzanthracene
- Formula: C20H16
- Molecular Weight: 256.35
DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models.
Nitrofurazone
- Formula: C6H6N4O4
- Molecular Weight: 198.14
Nitrofurazone (Nitrofural) is a broad spectrum antibiotic that has oral activity. Nitrofurazone is a nitro-aromatic drug. Nitrofurazone is active against both Gram-positive and Gram-negative bacteria.
