D-Mannose-13C6
Based on 1 Customer Validation
D-Mannose-13C6 is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific proteins.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 287100-74-7
- 分子式: 13C6H12O6
- 分子量:186.11
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 287100-74-7
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非標識Cas 3458-28-4
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性状 Solid
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分子量 186.11
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分子式 13C6H12O6
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Color White to off-white
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SMILES
O[13C@@H]([13C@@H]([13C@@H]([13CH]=O)O)O)[13C@@H]([13CH2]O)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
H2O : 250 mg/mL (1343.29 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Genovese C, et al. Effects of a new combination of plant extracts plus d-mannose for the management of uncomplicated recurrent urinary tract infections. J Chemother. 2018 Apr;30(2):107-114. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.3732 mL | 26.8658 mL | 53.7317 mL | 134.3292 mL |
| 5 mM | 1.0746 mL | 5.3732 mL | 10.7463 mL | 26.8658 mL | |
| 10 mM | 0.5373 mL | 2.6866 mL | 5.3732 mL | 13.4329 mL | |
| 15 mM | 0.3582 mL | 1.7911 mL | 3.5821 mL | 8.9553 mL | |
| 20 mM | 0.2687 mL | 1.3433 mL | 2.6866 mL | 6.7165 mL | |
| 25 mM | 0.2149 mL | 1.0746 mL | 2.1493 mL | 5.3732 mL | |
| 30 mM | 0.1791 mL | 0.8955 mL | 1.7911 mL | 4.4776 mL | |
| 40 mM | 0.1343 mL | 0.6716 mL | 1.3433 mL | 3.3582 mL | |
| 50 mM | 0.1075 mL | 0.5373 mL | 1.0746 mL | 2.6866 mL | |
| 60 mM | 0.0896 mL | 0.4478 mL | 0.8955 mL | 2.2388 mL | |
| 80 mM | 0.0672 mL | 0.3358 mL | 0.6716 mL | 1.6791 mL | |
| 100 mM | 0.0537 mL | 0.2687 mL | 0.5373 mL | 1.3433 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.