m-PEG12-NHS ester
Based on 1 Customer Validation
m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 2207596-93-6
- 分子式: C30H55NO16
- 分子量:685.75
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2207596-93-6
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性状 Solid
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分子量 685.75
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分子式 C30H55NO16
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Color White to off-white
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SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (145.83 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (264 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4583 mL | 7.2913 mL | 14.5826 mL | 36.4564 mL |
| 5 mM | 0.2917 mL | 1.4583 mL | 2.9165 mL | 7.2913 mL | |
| 10 mM | 0.1458 mL | 0.7291 mL | 1.4583 mL | 3.6456 mL | |
| 15 mM | 0.0972 mL | 0.4861 mL | 0.9722 mL | 2.4304 mL | |
| 20 mM | 0.0729 mL | 0.3646 mL | 0.7291 mL | 1.8228 mL | |
| 25 mM | 0.0583 mL | 0.2917 mL | 0.5833 mL | 1.4583 mL | |
| 30 mM | 0.0486 mL | 0.2430 mL | 0.4861 mL | 1.2152 mL | |
| 40 mM | 0.0365 mL | 0.1823 mL | 0.3646 mL | 0.9114 mL | |
| 50 mM | 0.0292 mL | 0.1458 mL | 0.2917 mL | 0.7291 mL | |
| 60 mM | 0.0243 mL | 0.1215 mL | 0.2430 mL | 0.6076 mL | |
| 80 mM | 0.0182 mL | 0.0911 mL | 0.1823 mL | 0.4557 mL | |
| 100 mM | 0.0146 mL | 0.0729 mL | 0.1458 mL | 0.3646 mL |
m-PEG12-NHS ester 関連分類
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